Diabetes combined with respiratory cardiovascular disease Which drugs can not be used?

Many people with diabetes suffer from other diseases, from colds to cardiovascular diseases. This will involve multiple medications. The mutual reaction of many drugs is really difficult to remember. This issue of Q&A is devoted to drugs that need to be used with caution in diabetic patients.

Diabetes combined with respiratory cardiovascular disease Which drugs can not be used?

When a diabetic patient has a respiratory illness such as a cold, which drugs cannot be used?

Diabetes patients with hypertension, which drugs can not be used?

Diabetes patients with high blood lipids, which drugs can not be used?

Diabetes patients with cardiovascular disease, which drugs can not be used?

Reference answer

Thin people have a higher risk of diabetes and cardiovascular disease

 A recent German survey found that nearly one-fifth of lean people are at high risk for diabetes and cardiovascular disease. These people are mainly fat-deficient, especially in the legs. The survey was completed by the German Diabetes Research Center and the Helmholtz Center and published in the professional journal Cell Metabolism.

Thin people have a higher risk of diabetes and cardiovascular disease

        People are used to thinking that slimness is healthy, but it is not entirely true. According to the sample survey, almost 20% of people with moderate body weight are sub-healthy people with metabolic problems, and their risk of cardiovascular disease and death is three times higher than that of people with metabolic health, even more than normal metabolism. Fat people are even higher.

        The researchers surveyed 981 thin people and found that 18% of the respondents had impaired metabolic function, mainly characterized by abdominal obesity, hypertension, hypertriglyceridemia, low-density lipoprotein cholesterol, and insulin resistance. And impaired glucose tolerance.

The essence of the recent association between diabetes and cardiovascular disease

Diabetes and cardiovascular and cerebrovascular diseases are the most common systemic diseases. Studies have confirmed that there is a close relationship between them, such as: diabetes people have almost all cardiovascular disease-related risk factors, such as hyperglycemia, dyslipidemia, high blood pressure and so on.

The essence of the recent association between diabetes and cardiovascular disease

1.JACC: bypass vsPCI--the choice of treatment for patients with cardiovascular disease of type 1 diabetes

For patients with type 1 diabetes (T1D) with multivessel disease, the greater benefit of bypass surgery or percutaneous coronary intervention (PCI) has not been elucidated.

This study included T1D patients who underwent the first multivessel reconstruction surgery in Sweden from 1995 to 2013, and conducted a comprehensive evaluation of the patient's clinical information and prognosis through multiple databases. Finally, a total of 683 patients undergoing bypass surgery and 1863 patients undergoing PCI were enrolled. After an average of 10.6 years of follow-up, 53% of patients in the bypass group and 45% of patients in the PCI group died, with bypass therapy. Compared with the group, all-cause mortality was similar in the PCI group (HR: 1.14; 95% CI: 0.99 - 1.32), and the risk of stroke and heart failure was similar, but coronary heart disease (HR: 1.45; 95% CI: The mortality rates of 1.21 - 1.74), myocardial infarction (HR: 1.47; 95% CI: 1.23 - 1.78) and revascularization (HR: 5.64; 95% CI: 4.67 - 6.82) were significantly higher.

The mortality rate of cardiovascular disease in diabetes is so high

Diabetic heart disease is a cardiovascular disease complicated or associated with diabetes, including diabetic cardiomyopathy, cardiovascular autonomic neuropathy, hypertension, and coronary heart disease. The incidence and mortality of cardiovascular disease in diabetic patients is 2-3 times higher than that in non-diabetic patients. The average life expectancy of cardiovascular disease and diabetes is 15 years. Diabetes is one of the more common diseases in the middle-aged and elderly population. Clinically, when the disease progresses to a certain stage, various complications will occur and the disease will be accelerated.

The mortality rate of cardiovascular disease in diabetes is so high

A study released by British researchers on the 7th showed that people with both cardiovascular disease and diabetes had an average lifespan of 15 years shorter than those with or without these two diseases. From 1960 to 2010, Cambridge University and other institutions collected 1.2 million volunteers and conducted long-term follow-up investigations on their health. With the help of big data, the researchers analyzed more than 135,000 deaths and estimated the proportion of people with diabetes, stroke, and myocardial infarction in the deceased, and compared it with other people.

2017 ESC experts understand diabetes and cardiovascular disease

The 2017 European Society of Cardiology Annual Meeting (ESC 2017) conducted a global webcast of the Symposium on Clinical Therapy for Type 2 Diabetes and Cardiovascular Diseases. Across the time and space, on the scene, listeners from more than 50 countries and regions listened to the experts' speech at ESC 2017 and experienced the latest diagnosis and treatment concepts related to type 2 diabetes and cardiovascular disease.

2017 ESC experts understand diabetes and cardiovascular disease

The conference was co-chaired by Professor Stefano Del Prato, an endocrinology and metabolism expert at the University of Pisa, Italy, and Professor Darren K. McGuire, a medical specialist at the University of Texas Southwestern Medical Center. He also invited Professor David Cherney, a nephrologist at the University of Toronto, Canada, and endocrine in the University of Toronto, Canada. Professor Lamrence Leiter, a metabolic expert, and four experts have conducted in-depth interpretation and discussion on the treatment of type 2 diabetes and cardiovascular disease.

Why is diabetes easy to cause cardiovascular disease?

Diabetes is a common group of metabolic endocrine diseases characterized by glucose and fat metabolism disorders and elevated plasma glucose levels. The pathogenesis and progression of the disease is very complicated, and there are still many scientists studying it.

Why is diabetes easy to cause cardiovascular disease?

Most people with diabetes can be classified into two major categories of pathogenesis. One type (type 1) is the absolute lack of insulin secretion, and the other type (type 2) is a combination of insulin resistance and insulin-compensatory secretory response. Because insulin is an important substance for lowering blood sugar secreted by the human body, in general, type 1 mainly refers to the problem of the formation of this substance, which does not reach a sufficient level. Type 2 mainly refers to the substance that acts on insulin is resistant to insulin, leading to insulin. Can not play the role of lowering blood sugar.