What are the dangers of diabetes on the heart?

What are the hazards of diabetes on the heart? High blood sugar is harmful to patients, and the most affected is the heart. Studies have shown that people with diabetes have a very high risk of heart disease. Common atherosclerosis is a serious threat to the health of sugar friends. So, what are the hazards of diabetes on the heart?

What are the dangers of diabetes on the heart?

The impact of diabetes on the heart:

Diabetes patients are bound to intensify their lipid and protein saccharification and oxidation due to long-term chronic hyperglycemia, and this process is also involved in the pathogenesis of diabetic heart disease. Many patients with type 2 diabetes have had coronary heart disease when they have just been diagnosed with type 2 diabetes. In the susceptible population of diabetes, insulin resistance is the first change. It can occur 15 to 25 years before clinical diabetes. Insulin resistance is associated with a risk factor for atherosclerosis, which promotes atherosclerosis for many years before the onset of clinical diabetes.


Pathological anatomical studies have shown that diabetic patients have more severe atherosclerosis than non-diabetic patients of the same age in the coronary arteries, cerebral arteries, renal arteries, and peripheral arteries.

After atherosclerosis, part or all of the lumen is blocked, resulting in ischemia of the target organs and hypoxia. If the lesion is blocked in the coronary artery, it causes coronary atherosclerotic heart disease (coronary heart disease). Compared with patients with coronary heart disease without diabetes, the former patients generally have multiple coronary vessels involved, and the lesions are widely dispersed, with more plaque ulcers and thrombosis. Diabetes accelerates the progression of atherosclerosis at any age, similar in countries around the world.

The mechanism by which diabetes causes atherosclerosis is multifaceted. In the case of hyperglycemia alone, irreversible glycated proteins and glycated lipoproteins can be formed, which increases the degree of oxidative damage, and can also cause damage to the blood vessel wall and endothelium, and promote thrombosis.

Diabetes can also cause microvascular disease, endothelial damage, thickening of the basement membrane, non-enzymatic glycation of proteins, increased free radical activity, and abnormal prostaglandins.

The main cause of death from cardiovascular disease into sugar friends:

Among all diabetes-related deaths, cardiovascular disease has become a major complication and the leading cause of death in diabetic patients.

Experts pointed out that macrovascular complications are the leading cause of death in diabetic patients. A 22-year follow-up study in the United States found that about 65 percent of people with diabetes died of cardiovascular and cerebrovascular disease, and 41 percent of them died of ischemic heart disease. "Diabetes is an independent risk factor for cardiovascular disease. The risk of cardiovascular disease in diabetic patients is not only increased, but the disease is severely changed, more extensive, the prognosis is worse, and the age of onset is earlier." A long-term follow-up study showed that male sugar users had a 2-fold increased risk of cardiovascular and cerebrovascular disease compared with those without diabetes, and female sugar friends increased by 4 to 5 times.